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Glutathione deficiency increases hepatic ascorbic acid synthesis in adult mice.

Glutathione deficiency, induced in adult mice by administering buthionine sulfoximine (an inhibitor of glutathione synthesis), led to a rapid and substantial increase in ascorbate in the liver. This effect was apparent 2-4 hr after giving the inhibitor; subsequently, the level of ascorbate decreased...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Mårtensson, J, Meister, A
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1992
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50593/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1454849/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.23.11566
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