Therapeutic Administration of a Monoclonal Anti-Il-1β Antibody Protects Against Experimental Melioidosis

BACKGROUND: Melioidosis, caused by the gram-negative bacterium Burkholderia pseudomallei, is a common cause of community-acquired sepsis in Southeast Asia and Northern Australia. The NLRP3 inflammasome and its downstream product interleukin-1 beta (IL-1β) have been proposed to play crucial roles in...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Shock
Egile Nagusiak: Weehuizen, Tassili A. F., Lankelma, Jacqueline M., De Jong, Hanna K., De Boer, Onno J., Roelofs, Joris J. T. H., Day, Nicholas P., Gram, Hermann, De Vos, Alex F., Wiersinga, W. Joost
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Lippincott Williams & Wilkins 2016
Gaiak:
Basic Science Aspects
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058638/
https://ncbi.nlm.nih.gov/pubmed/27219859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000625
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