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Targeted immunotherapy using anti-CD138-interferon α fusion proteins and bortezomib results in synergistic protection against multiple myeloma

Although recent advances have substantially improved the management of multiple myeloma, it remains an incurable malignancy. We now demonstrate that anti-CD138 molecules genetically fused to type I interferons (IFN) synergize with the approved therapeutic bortezomib in arresting the proliferation of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:MAbs
Hauptverfasser: Vasuthasawat, Alex, Yoo, Esther M., Trinh, Kham R., Lichtenstein, Alan, Timmerman, John M., Morrison, Sherie L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058616/
https://ncbi.nlm.nih.gov/pubmed/27362935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1207030
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