Activity of Anti-CD19 Chimeric Antigen Receptor T Cells Against B Cell Lymphoma Is Enhanced by Antibody-Targeted Interferon-Alpha

An important emerging form of immunotherapy targeting B cell malignancies is chimeric antigen receptor (CAR) T cell therapy. Despite encouraging response rates of anti-CD19 CAR T cell therapy in B cell lymphomas, limited durability of response necessitates further study to potentiate CAR T cell effi...

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Detalhes bibliográficos
Publicado no:J Interferon Cytokine Res
Main Authors: Young, Patricia A., Yamada, Reiko E., Trinh, Kham R., Vasuthasawat, Alex, De Oliveira, Satiro, Yamada, Douglas H., Morrison, Sherie L., Timmerman, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2018
Assuntos:
Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007814/
https://ncbi.nlm.nih.gov/pubmed/29920129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2018.0030
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