Betulin attenuates atherosclerosis in apoE(−/−) mice by up-regulating ABCA1 and ABCG1

AIM: Betulin is a pentacyclic triterpenoid isolated from the bark of yellow and white birch trees with anti-cancer and anti-malaria activities. In this study we examined the effects of betulin on atherosclerosis in apoE(−/−) mice and the underlying mechanisms. METHODS: Murine macrophage RAW264.7 cel...

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Publicado en:Acta Pharmacol Sin
Main Authors: Gui, Yu-zhou, Yan, Hong, Gao, Fei, Xi, Cong, Li, Hui-hui, Wang, Yi-ping
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5057233/
https://ncbi.nlm.nih.gov/pubmed/27374487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.46
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