Deficiency of ABCA1 and ABCG1 in Macrophages Increases Inflammation and Accelerates Atherosclerosis in Mice

RATIONALE: Plasma HDL levels are inversely correlated with atherosclerosis. Although it is widely assumed that this is due to the ability of HDL to promote cholesterol efflux from macrophage foam cells, direct experimental support for this hypothesis is lacking. OBJECTIVE: To assess the role of macr...

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Detalhes bibliográficos
Main Authors: Westerterp, Marit, Murphy, Andrew J., Wang, Mi, Pagler, Tamara A., Vengrenyuk, Yuliya, Kappus, Mojdeh S., Gorman, Darren J., Nagareddy, Prabhakara R., Zhu, Xuewei, Abramowicz, Sandra, Parks, John S., Welch, Carrie, Fisher, Edward A., Wang, Nan, Yvan-Charvet, Laurent, Tall, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839866/
https://ncbi.nlm.nih.gov/pubmed/23572498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.113.301086
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