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Activation of Liver X Receptor Decreases Atherosclerosis in Ldlr(−/−) mice in the Absence of ABCA1 and ABCG1 in Myeloid Cells
OBJECTIVE: Liver X Receptor (LXR) activators decrease atherosclerosis in mice. LXR activators (1) directly up-regulate genes involved in reverse cholesterol transport (RCT) and (2) exert anti-inflammatory effects mediated by transrepression of NFκB target genes. We investigated whether myeloid cell...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3941179/ https://ncbi.nlm.nih.gov/pubmed/24311381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.302781 |
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