Deletion of ABCA1 and ABCG1 Impairs Macrophage Migration Because of Increased Rac1 Signaling

RATIONALE: Reduced plasma cholesterol and increased high-density lipoprotein (HDL) levels promote regression of atherosclerosis, in a process characterized by lipid unloading and emigration of macrophages from lesions. In contrast free cholesterol loading of macrophages leads to imbalanced Rac1/Rho...

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Detalhes bibliográficos
Main Authors: Pagler, Tamara A., Wang, Mi, Mondal, Mousumi, Murphy, Andrew J., Westerterp, Marit, Moore, Kathryn J., Maxfield, Frederick R., Tall, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097897/
https://ncbi.nlm.nih.gov/pubmed/21148432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.228619
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