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Effects of TORC1 Inhibition during the Early and Established Phases of Polycystic Kidney Disease

The disease-modifying effects of target of rapamycin complex 1 (TORC1) inhibitors during different stages of polycystic kidney disease (PKD) are not well defined. In this study, male Lewis Polycystic Kidney Disease (LPK) rats (a genetic ortholog of human NPHP9, phenotypically characterised by diffus...

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Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Ta, Michelle H. T., Schwensen, Kristina G., Foster, Sheryl, Korgaonkar, Mayuresh, Ozimek-Kulik, Justyna E., Phillips, Jacqueline K., Peduto, Anthony, Rangan, Gopala K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056751/
https://ncbi.nlm.nih.gov/pubmed/27723777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164193
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