Pyrrolidine dithiocarbamate reduces the progression of total kidney volume and cyst enlargement in experimental polycystic kidney disease

Heterocyclic dithiocarbamates have anti‐inflammatory and anti‐proliferative effects in rodent models of chronic kidney disease. In this study, we tested the hypothesis that pyrrolidine dithiocarbamate (PDTC) reduces the progression of polycystic kidney disease (PKD). Male Lewis polycystic kidney (LP...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Ta, Michelle H. T., Rao, Padmashree, Korgaonkar, Mayuresh, Foster, Sheryl F., Peduto, Anthony, Harris, David C. H., Rangan, Gopala K.
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Periodicals, Inc. 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332200/
https://ncbi.nlm.nih.gov/pubmed/25501440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12196
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