Regression of Peritubular Capillaries Coincides with Angiogenesis and Renal Cyst Growth in Experimental Polycystic Kidney Disease

BACKGROUND/AIM: The natural history of the renal microvasculature changes in PKD is not known. The aim of this study was to test the hypothesis that angiogenesis is coupled with kidney cyst expansion, and the loss of peritubular capillary networks precedes the onset of interstitial fibrosis. METHODS...

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Bibliografski detalji
Izdano u:Int J Nephrol Renovasc Dis
Glavni autori: O’Brien, Kristal, Saravanabavan, Sayanthooran, Zhang, Jennifer Q J, Wong, Annette T Y, Munt, Alexandra, Burgess, Jane S, Rangan, Gopala K
Format: Artigo
Jezik:Inglês
Izdano: Dove 2020
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7132028/
https://ncbi.nlm.nih.gov/pubmed/32280260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJNRD.S238767
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