Pyrrolidine dithiocarbamate reduces the progression of total kidney volume and cyst enlargement in experimental polycystic kidney disease

Heterocyclic dithiocarbamates have anti‐inflammatory and anti‐proliferative effects in rodent models of chronic kidney disease. In this study, we tested the hypothesis that pyrrolidine dithiocarbamate (PDTC) reduces the progression of polycystic kidney disease (PKD). Male Lewis polycystic kidney (LP...

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Veröffentlicht in:Physiol Rep
Hauptverfasser: Ta, Michelle H. T., Rao, Padmashree, Korgaonkar, Mayuresh, Foster, Sheryl F., Peduto, Anthony, Harris, David C. H., Rangan, Gopala K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley Periodicals, Inc. 2014
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332200/
https://ncbi.nlm.nih.gov/pubmed/25501440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12196
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