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Cytokinetic effects of Wee1 disruption in pancreatic cancer
The Wee1 kinase, which is activated in response to DNA damage, regulates exit from G2 through inhibitory phosphorylation of Cdk1/Cdc2, and is an attractive drug target. However, recent work has highlighted effects of Cdk2 phosphorylation by Wee1 on movement through S-phase, suggesting the potential...
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Gepubliceerd in: | Cell Cycle |
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Hoofdauteurs: | , , , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Taylor & Francis
2016
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5056606/ https://ncbi.nlm.nih.gov/pubmed/26890070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1138188 |
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