Glycogen synthase kinase-3 inhibition disrupts nuclear factor-kappaB activity in pancreatic cancer, but fails to sensitize to gemcitabine chemotherapy

Por Mamaghani, Shadi, Patel, Satish, Hedley, David W
Publicado em 2009

Antitumour activity of a potent MEK inhibitor RDEA119/BAY 869766 combined with rapamycin in human orthotopic primary pancreatic cancer xenografts

Por Miner Jeffrey N, Chapman Mark S, Chang Qing, Hedley David W
Publicado em 2010-09-01

Antitumour activity of a potent MEK inhibitor RDEA119/BAY 869766 combined with rapamycin in human orthotopic primary pancreatic cancer xenografts

Por Chang, Qing, Chapman, Mark S, Miner, Jeffrey N, Hedley, David W
Publicado em 2010

Cytokinetic effects of Wee1 disruption in pancreatic cancer

Por Chang, Qing, Chandrashekhar, Megha, Ketela, Troy, Fedyshyn, Yaroslav, Moffat, Jason, Hedley, David
Publicado no Cell Cycle (2016)

Hedgehog inhibition enhances efficacy of radiation and cisplatin in orthotopic cervical cancer xenografts

Por Chaudary, Naz, Pintilie, Melania, Hedley, David, Hill, Richard P, Milosevic, Michael, Mackay, Helen
Publicado no Br J Cancer (2017)

Immunohistochemical analysis of changes in signaling pathway activation downstream of growth factor receptors in pancreatic duct cell carcinogenesis

Por Pham, Nhu-An, Schwock, Joerg, Iakovlev, Vladimir, Pond, Greg, Hedley, David W, Tsao, Ming-Sound
Publicado em 2008

Assessment of Hypoxia in the Stroma of Patient-Derived Pancreatic Tumor Xenografts

Por Lohse, Ines, Lourenco, Corey, Ibrahimov, Emin, Pintilie, Melania, Tsao, Ming-Sound, Hedley, David W.
Publicado em 2014

Cancer initiating-cells are enriched in the CA9 positive fraction of primary cervix cancer xenografts

Por Marie-Egyptienne, Delphine Tamara, Chaudary, Naz, Kalliomäki, Tuula, Hedley, David William, Hill, Richard Peter
Publicado no Oncotarget (2016)

Activity of the novel polo-like kinase 4 inhibitor CFI-400945 in pancreatic cancer patient-derived xenografts

Por Lohse, Ines, Mason, Jacqueline, Mary, Pinjiang Cao, Pintilie, Melania, Bray, Mark, Hedley, David W
Publicado no Oncotarget (2016)

Biodistribution of cisplatin revealed by imaging mass cytometry identifies extensive collagen binding in tumor and normal tissues

Por Chang, Qing, Ornatsky, Olga I., Siddiqui, Iram, Straus, Rita, Baranov, Vladimir I., Hedley, David W.
Publicado no Sci Rep (2016)

Effects of Combined Treatment with Ionizing Radiation and the PARP Inhibitor Olaparib in BRCA Mutant and Wild Type Patient-Derived Pancreatic Cancer Xenografts

Por Lohse, Ines, Kumareswaran, Ramya, Cao, Pinjiang, Pitcher, Bethany, Gallinger, Steven, Bristow, Robert G., Hedley, David W.
Publicado no PLoS One (2016)

Up-Regulation of the Redox Mediators Thioredoxin and Apurinic/Apyrimidinic Excision (APE)/Ref-1 in Hypoxic Microregions of Invasive Cervical Carcinomas, Mapped Using Multispectral,...

Por Hedley, David, Pintilie, Melania, Woo, Jennifer, Nicklee, Trudey, Morrison, Andrew, Birle, Diana, Fyles, Anthony, Milosevic, Michael, Hill, Richard
Publicado em 2004

Quantitative image analysis of immunohistochemical stains using a CMYK color model

Por Pham, Nhu-An, Morrison, Andrew, Schwock, Joerg, Aviel-Ronen, Sarit, Iakovlev, Vladimir, Tsao, Ming-Sound, Ho, James, Hedley, David W
Publicado em 2007

SNAI1 expression and the mesenchymal phenotype: an immunohistochemical study performed on 46 cases of oral squamous cell carcinoma

Por Schwock, Joerg, Bradley, Grace, Ho, James C, Perez-Ordonez, Bayardo, Hedley, David W, Irish, Jonathan C, Geddie, William R
Publicado em 2010

Targeting hypoxic microenvironment of pancreatic xenografts with the hypoxia-activated prodrug TH-302

Por Lohse, Ines, Rasowski, Joanna, Cao, Pinjiang, Pintilie, Melania, Do, Trevor, Tsao, Ming-Sound, Hill, Richard P., Hedley, David W.
Publicado no Oncotarget (2016)

Glycogen Synthase Kinase-3 Inhibition Sensitizes Pancreatic Cancer Cells to TRAIL-Induced Apoptosis

Por Mamaghani, Shadi, Simpson, Craig D., Cao, Pinjiang M., Cheung, May, Chow, Sue, Bandarchi, Bizhan, Schimmer, Aaron D., Hedley, David W.
Publicado em 2012

Targeting of metastasis-promoting tumor-associated fibroblasts and modulation of pancreatic tumor-associated stroma with a carboxymethylcellulose-docetaxel nanoparticle

Por Ernsting, Mark J., Hoang, Bryan, Lohse, Ines, Undzys, Elijus, Cao, Pinjiang, Do, Trevor, Gill, Bethany, Pintilie, Melania, Hedley, David, Li, Shyh-Dar
Publicado no J Control Release (2015)

FOLFIRINOX for advanced pancreatic cancer: the Princess Margaret Cancer Centre experience

Por Chllamma, Muralidharan K, Cook, Natalie, Dhani, Neesha C, Giby, Kazim, Dodd, Anna, Wang, Lisa, Hedley, David W, Moore, Malcolm J, Knox, Jennifer J
Publicado no Br J Cancer (2016)

Novel regulatory role of neuropilin-1 in endothelial-to-mesenchymal transition and fibrosis in pancreatic ductal adenocarcinoma

Por Matkar, Pratiek N., Singh, Krishna Kumar, Rudenko, Dmitriy, Kim, Yu Jin, Kuliszewski, Michael A., Prud'homme, Gerald J., Hedley, David W., Leong-Poi, Howard
Publicado no Oncotarget (2016)

Down-Regulation of Rad51 and Decreased Homologous Recombination in Hypoxic Cancer Cells

Por Bindra, Ranjit S., Schaffer, Paul J., Meng, Alice, Woo, Jennifer, Måseide, Kårstein, Roth, Matt E., Lizardi, Paul, Hedley, David W., Bristow, Robert G., Glazer, Peter M.
Publicado em 2004