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SNAI1 expression and the mesenchymal phenotype: an immunohistochemical study performed on 46 cases of oral squamous cell carcinoma

BACKGROUND: SNAI1 can initiate epithelial-mesenchymal transition (EMT), leading to loss of epithelial characteristics and, in cancer, to invasion and metastasis. We hypothesized that SNAI1 reactivation occurs in oral squamous cell carcinoma (OSCC) where it might also be associated with focal adhesio...

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Detalhes bibliográficos
Main Authors: Schwock, Joerg, Bradley, Grace, Ho, James C, Perez-Ordonez, Bayardo, Hedley, David W, Irish, Jonathan C, Geddie, William R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829523/
https://ncbi.nlm.nih.gov/pubmed/20181105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6890-10-1
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