Proteomic analysis of FUS interacting proteins provides insights into FUS function and its role in ALS

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease. Mutations in the Fused in Sarcoma/Translocated in Liposarcoma (FUS/TLS) gene cause a subset of familial ALS cases and are also implicated in sporadic ALS. FUS is typically localized to the nucleus. The ALS-related FUS mu...

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Bibliographic Details
Published in:Biochim Biophys Acta
Main Authors: Kamelgarn, Marisa, Chen, Jing, Kuang, Lisha, Arenas, Alexandra, Zhai, Jianjun, Zhu, Haining, Gal, Jozsef
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055831/
https://ncbi.nlm.nih.gov/pubmed/27460707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2016.07.015
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