Lysine acetylation regulates the RNA binding, subcellular localization and inclusion formation of FUS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the preferential death of motor neurons. Approximately 10% of ALS cases are familial and 90% are sporadic. Fused in sarcoma (FUS) is a ubiquitously expressed RNA-binding protein implicated in familial ALS and frontot...

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Detaylı Bibliyografya
Yayımlandı:Hum Mol Genet
Asıl Yazarlar: Arenas, Alexandra, Chen, Jing, Kuang, Lisha, Barnett, Kelly R, Kasarskis, Edward J, Gal, Jozsef, Zhu, Haining
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2020
Konular:
General Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530527/
https://ncbi.nlm.nih.gov/pubmed/32691043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa159
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