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Lysine acetylation regulates the RNA binding, subcellular localization and inclusion formation of FUS
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the preferential death of motor neurons. Approximately 10% of ALS cases are familial and 90% are sporadic. Fused in sarcoma (FUS) is a ubiquitously expressed RNA-binding protein implicated in familial ALS and frontot...
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| Publicado no: | Hum Mol Genet |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7530527/ https://ncbi.nlm.nih.gov/pubmed/32691043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa159 |
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