Lysine acetylation regulates the RNA binding, subcellular localization and inclusion formation of FUS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the preferential death of motor neurons. Approximately 10% of ALS cases are familial and 90% are sporadic. Fused in sarcoma (FUS) is a ubiquitously expressed RNA-binding protein implicated in familial ALS and frontot...

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發表在:Hum Mol Genet
Main Authors: Arenas, Alexandra, Chen, Jing, Kuang, Lisha, Barnett, Kelly R, Kasarskis, Edward J, Gal, Jozsef, Zhu, Haining
格式: Artigo
語言:Inglês
出版: Oxford University Press 2020
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General Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530527/
https://ncbi.nlm.nih.gov/pubmed/32691043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa159
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