Endothelin-1 Overexpression Exaggerates Diabetes-Induced Endothelial Dysfunction by Altering Oxidative Stress

BACKGROUND: Increased endothelin (ET)-1 expression causes endothelial dysfunction and oxidative stress. Plasma ET-1 is increased in patients with diabetes mellitus. Since endothelial dysfunction often precedes vascular complications in diabetes, we hypothesized that overexpression of ET-1 in the end...

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Vydáno v:Am J Hypertens
Hlavní autoři: Idris-Khodja, Noureddine, Ouerd, Sofiane, Mian, Muhammad Oneeb Rehman, Gornitsky, Jordan, Barhoumi, Tlili, Paradis, Pierre, Schiffrin, Ernesto L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055737/
https://ncbi.nlm.nih.gov/pubmed/27465439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajh/hpw078
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