ALDOSTERONE-INDUCED VASCULAR REMODELING AND ENDOTHELIAL DYSFUNCTION REQUIRE FUNCTIONAL ANGIOTENSIN TYPE 1a RECEPTORS

We investigated the role of angiotensin type 1a receptors (AGTR1a) in vascular injury induced by aldosterone activation of mineralocorticoid receptors (MR) in Agtr1a(−/−) and wild-type mice infused with aldosterone for 14 days while receiving 1% NaCl in drinking water. Aldosterone increased systolic...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Briet, Marie, Barhoumi, Tlili, Mian, Muhammad Oneeb Rehman, Coelho, Suellen C., Ouerd, Sofiane, Rautureau, Yohann, Coffman, Thomas M., Paradis, Pierre, Schiffrin, Ernesto L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833572/
https://ncbi.nlm.nih.gov/pubmed/27045029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.115.07074
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