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Vascular smooth muscle cell peroxisome proliferator-activated receptor γ protects against endothelin-1-induced oxidative stress and inflammation
AIMS: Peroxisome proliferator-activated receptor γ (PPAR(γ)) agonists reduce blood pressure and vascular injury in hypertensive rodents. Pparγ inactivation in vascular smooth muscle cells (VSMC) enhances vascular injury. Transgenic mice overexpressing endothelin (ET)-1 selectively in the endothelium...
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| Publicado no: | J Hypertens |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6338076/ https://ncbi.nlm.nih.gov/pubmed/28234672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0000000000001324 |
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