Vascular smooth muscle cell peroxisome proliferator-activated receptor γ protects against endothelin-1-induced oxidative stress and inflammation

AIMS: Peroxisome proliferator-activated receptor γ (PPAR(γ)) agonists reduce blood pressure and vascular injury in hypertensive rodents. Pparγ inactivation in vascular smooth muscle cells (VSMC) enhances vascular injury. Transgenic mice overexpressing endothelin (ET)-1 selectively in the endothelium...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Hypertens
Prif Awduron: Idris-Khodja, Noureddine, Ouerd, Sofiane, Trindade, Michelle, Gornitsky, Jordan, Rehman, Asia, Barhoumi, Tlili, Offermanns, Stefan, Gonzalez, Frank J., Neves, Mario F., Paradis, Pierre, Schiffrin, Ernesto L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338076/
https://ncbi.nlm.nih.gov/pubmed/28234672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0000000000001324
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