Endothelium-restricted endothelin-1 overexpression in type 1 diabetes worsens atherosclerosis and immune cell infiltration via NOX1

AIMS: NADPH oxidase (NOX) 1 but not NOX4-dependent oxidative stress plays a role in diabetic vascular disease, including atherosclerosis. Endothelin (ET)-1 has been implicated in diabetes-induced vascular complications. We showed that crossing mice overexpressing human ET-1 selectively in endotheliu...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Ouerd, Sofiane, Idris-Khodja, Noureddine, Trindade, Michelle, Ferreira, Nathanne S, Berillo, Olga, Coelho, Suellen C, Neves, Mario F, Jandeleit-Dahm, Karin A, Paradis, Pierre, Schiffrin, Ernesto L
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983005/
https://ncbi.nlm.nih.gov/pubmed/32533834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvaa168
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