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Structural reverse genetics study of the PI5P4Kβ–nucleotide complexes reveals the presence of the GTP bioenergetic system in mammalian cells

Reverse genetic analysis can connect a gene and its protein counterpart to a biological function(s) by knockout or knockdown of the specific gene. However, when a protein has multiple biochemical activities, the conventional genetics strategy is incapable of distinguishing which biochemical activity...

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Detalhes bibliográficos
Publicado no:FEBS J
Main Authors: Takeuchi, Koh, Senda, Miki, Lo, Yu-Hua, Kofuji, Satoshi, Ikeda, Yoshiki, Sasaki, Atsuo T., Senda, Toshiya
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053874/
https://ncbi.nlm.nih.gov/pubmed/27090388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13739
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