Divergent Mechanisms Activating RAS and Small GTPases Through Post-translational Modification

RAS is a founding member of the RAS superfamily of GTPases. These small 21 kDa proteins function as molecular switches to initialize signaling cascades involved in various cellular processes, including gene expression, cell growth, and differentiation. RAS is activated by GTP loading and deactivated...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Osaka, Natsuki, Hirota, Yoshihisa, Ito, Doshun, Ikeda, Yoshiki, Kamata, Ryo, Fujii, Yuki, Chirasani, Venkat R., Campbell, Sharon L., Takeuchi, Koh, Senda, Toshiya, Sasaki, Atsuo T.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Molecular Biosciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8295990/
https://ncbi.nlm.nih.gov/pubmed/34307463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.707439
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