Resistance of ground glass hepatocytes to oral antivirals in chronic hepatitis B patients and implication for the development of hepatocellular carcinoma

Ground glass hepatocytes (GGHs) have been shown to predict the development of hepatocellular carcinoma (HCC). Type I GGH and type II GGH harbor hepatitis B virus (HBV) pre-S1 and pre-S2 deletion mutants, respectively. Whether anti-HBV therapy can inhibit the expression of GGHs and potentially reduce...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Tsai, Hung-Wen, Lin, Yih-Jyh, Wu, Han-Chieh, Chang, Ting-Tsung, Wu, I-Chin, Cheng, Pin-Nan, Yen, Chia-Jui, Chan, Shih-Huang, Huang, Wenya, Su, Ih-Jen
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053683/
https://ncbi.nlm.nih.gov/pubmed/27027237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8388
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