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A pre-S gene chip to detect pre-S deletions in hepatitis B virus large surface antigen as a predictive marker for hepatoma risk in chronic hepatitis B virus carriers

BACKGROUND: Chronic hepatitis B virus (HBV) infection is an important cause of hepatocellular carcinoma (HCC) worldwide. The pre-S(1 )and -S(2 )mutant large HBV surface antigen (LHBS), in which the pre-S(1 )and -S(2 )regions of the LHBS gene are partially deleted, are highly associated with HBV-rela...

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Hlavní autoři: Shen, Fan-Ching, Su, Ih-Jen, Wu, Han-Chieh, Hsieh, Yi-Hsuan, Yao, Wei-Jen, Young, Kung-Chia, Chang, Tsung-Chuan, Hsieh, Hui-Chuan, Tsai, Han-Ni, Huang, Wenya
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755474/
https://ncbi.nlm.nih.gov/pubmed/19751529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-16-84
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