Hepatitis B Virus Pre-S2 Mutant Induces Aerobic Glycolysis through Mammalian Target of Rapamycin Signal Cascade

Hepatitis B virus (HBV) pre-S2 mutant can induce hepatocellular carcinoma (HCC) via the induction of endoplasmic reticulum stress to activate mammalian target of rapamycin (MTOR) signaling. The association of metabolic syndrome with HBV-related HCC raises the possibility that pre-S2 mutant-induced M...

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Udgivet i:PLoS One
Main Authors: Teng, Chiao-Fang, Hsieh, Wen-Chuan, Wu, Han-Chieh, Lin, Yih-Jyh, Tsai, Hung-Wen, Huang, Wenya, Su, Ih-Jen
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409318/
https://ncbi.nlm.nih.gov/pubmed/25909713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122373
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