Lipid Storage and Interferon Response Determine the Phenotype of Ground Glass Hepatocytes in Mice and Humans

BACKGROUND AND AIMS: A histopathological hallmark of chronic hepatitis B virus (HBV) infection is the presence of ground glass hepatocytes (GGHs). GGHs are liver cells that exhibit eosinophilic, granular, glassy cytoplasm in light microscopy and are characterized by accumulation of HBV surface (HBs)...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Churin, Yuri, Irungbam, Karuna, Imiela, Christoph S., Schwarz, David, Mollenkopf, Hans-Joachim, Drebber, Uta, Odenthal, Margarete, Pak, Oleg, Huber, Magdalena, Glebe, Dieter, Roderfeld, Martin, Roeb, Elke
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8255940/
https://ncbi.nlm.nih.gov/pubmed/33766783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2021.03.009
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