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The degree of intratumor mutational heterogeneity varies by primary tumor sub-site

In an era where mutational profiles inform treatment options, it is critical to know the extent to which tumor biopsies represent the molecular profile of the primary and metastatic tumor. Head and neck squamous cell carcinoma (HNSCC) arise primarily in the mucosal lining of oral cavity and orophary...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ledgerwood, Levi G., Kumar, Dhruv, Eterovic, Agda Karina, Wick, Jo, Chen, Ken, Zhao, Hao, Tazi, Loubna, Manna, Pradip, Kerley, Spencer, Joshi, Radhika, Wang, Lin, Chiosea, Simion I., Garnett, James David, Tsue, Terance Ted, Chien, Jeremy, Mills, Gordon B., Grandis, Jennifer Rubin, Thomas, Sufi Mary
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053641/
https://ncbi.nlm.nih.gov/pubmed/27034009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8448
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