The degree of intratumor mutational heterogeneity varies by primary tumor sub-site

In an era where mutational profiles inform treatment options, it is critical to know the extent to which tumor biopsies represent the molecular profile of the primary and metastatic tumor. Head and neck squamous cell carcinoma (HNSCC) arise primarily in the mucosal lining of oral cavity and orophary...

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Publicado en:Oncotarget
Autores principales: Ledgerwood, Levi G., Kumar, Dhruv, Eterovic, Agda Karina, Wick, Jo, Chen, Ken, Zhao, Hao, Tazi, Loubna, Manna, Pradip, Kerley, Spencer, Joshi, Radhika, Wang, Lin, Chiosea, Simion I., Garnett, James David, Tsue, Terance Ted, Chien, Jeremy, Mills, Gordon B., Grandis, Jennifer Rubin, Thomas, Sufi Mary
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053641/
https://ncbi.nlm.nih.gov/pubmed/27034009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8448
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