The degree of intratumor mutational heterogeneity varies by primary tumor sub-site

In an era where mutational profiles inform treatment options, it is critical to know the extent to which tumor biopsies represent the molecular profile of the primary and metastatic tumor. Head and neck squamous cell carcinoma (HNSCC) arise primarily in the mucosal lining of oral cavity and orophary...

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Udgivet i:Oncotarget
Main Authors: Ledgerwood, Levi G., Kumar, Dhruv, Eterovic, Agda Karina, Wick, Jo, Chen, Ken, Zhao, Hao, Tazi, Loubna, Manna, Pradip, Kerley, Spencer, Joshi, Radhika, Wang, Lin, Chiosea, Simion I., Garnett, James David, Tsue, Terance Ted, Chien, Jeremy, Mills, Gordon B., Grandis, Jennifer Rubin, Thomas, Sufi Mary
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053641/
https://ncbi.nlm.nih.gov/pubmed/27034009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8448
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