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TBP loading by AF4 through SL1 is the major rate-limiting step in MLL fusion-dependent transcription
Gene rearrangement of the mixed lineage leukemia (MLL) gene causes leukemia by inducing the constitutive expression of a gene subset normally expressed only in the immature haematopoietic progenitor cells. MLL gene rearrangements often generate fusion products of MLL and a component of the AF4 famil...
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| Publicado no: | Cell Cycle |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5053588/ https://ncbi.nlm.nih.gov/pubmed/27564129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1222337 |
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