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Retroviral integration: Site matters: Mechanisms and consequences of retroviral integration site selection

Here, we review genomic target site selection during retroviral integration as a multistep process in which specific biases are introduced at each level. The first asymmetries are introduced when the virus takes a specific route into the nucleus. Next, by co‐opting distinct host cofactors, the integ...

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Vydáno v:Bioessays
Hlavní autoři: Demeulemeester, Jonas, De Rijck, Jan, Gijsbers, Rik, Debyser, Zeger
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053271/
https://ncbi.nlm.nih.gov/pubmed/26293289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201500051
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