The BET family of proteins targets Moloney Murine Leukemia Virus integration near transcription start sites

A hallmark of retroviral replication is integration of the viral genome in the host cell DNA. This characteristic makes retrovirus-based vectors attractive delivery vehicles for gene therapy. However, adverse events in gene therapeutic trials, caused by activation of proto-oncogenes due to Murine Le...

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Detalhes bibliográficos
Main Authors: De Rijck, Jan, de Kogel, Christine, Demeulemeester, Jonas, Vets, Sofie, Ashkar, Sara El, Malani, Nirav, Bushman, Frederic D, Landuyt, Bart, Husson, Steven J., Busschots, Katrien, Gijsbers, Rik, Debyser, Zeger
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197836/
https://ncbi.nlm.nih.gov/pubmed/24183673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.09.040
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