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The BET family of proteins targets Moloney Murine Leukemia Virus integration near transcription start sites
A hallmark of retroviral replication is integration of the viral genome in the host cell DNA. This characteristic makes retrovirus-based vectors attractive delivery vehicles for gene therapy. However, adverse events in gene therapeutic trials, caused by activation of proto-oncogenes due to Murine Le...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4197836/ https://ncbi.nlm.nih.gov/pubmed/24183673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.09.040 |
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