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BET-independent MLV-based Vectors Target Away From Promoters and Regulatory Elements
Stable integration in the host genome renders murine leukemia virus (MLV)-derived vectors attractive tools for gene therapy. Adverse events in otherwise successful clinical trials caused by proto-oncogene activation due to vector integration hamper their application. MLV and MLV-based vectors integr...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4121521/ https://ncbi.nlm.nih.gov/pubmed/25072693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2014.33 |
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