LEDGF Hybrids Efficiently Retarget Lentiviral Integration Into Heterochromatin

Correction of genetic diseases requires integration of the therapeutic gene copy into the genome of patient cells. Retroviruses are commonly used as delivery vehicles because of their precise integration mechanism, but their use has led to adverse events in which vector integration activated proto-o...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Gijsbers, Rik, Ronen, Keshet, Vets, Sofie, Malani, Nirav, De Rijck, Jan, McNeely, Melissa, Bushman, Frederic D, Debyser, Zeger
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839429/
https://ncbi.nlm.nih.gov/pubmed/20195265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.36
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars