تحميل...
LEDGF Hybrids Efficiently Retarget Lentiviral Integration Into Heterochromatin
Correction of genetic diseases requires integration of the therapeutic gene copy into the genome of patient cells. Retroviruses are commonly used as delivery vehicles because of their precise integration mechanism, but their use has led to adverse events in which vector integration activated proto-o...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Nature Publishing Group
2010
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2839429/ https://ncbi.nlm.nih.gov/pubmed/20195265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.36 |
| الوسوم: |
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