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Integration Site Selection by Retroviral Vectors: Molecular Mechanism and Clinical Consequences

Retroviral DNA integration into the host cell genome is an essential feature of the retroviral life cycle. The ability to integrate their DNA into the DNA of infected cells also makes retroviruses attractive vectors for delivery of therapeutic genes into the genome of cells carrying adverse mutation...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Daniel, René, Smith, Johanna A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940482/
https://ncbi.nlm.nih.gov/pubmed/18533894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2007.148
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