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Deciphering the Code for Retroviral Integration Target Site Selection

Upon cell invasion, retroviruses generate a DNA copy of their RNA genome and integrate retroviral cDNA within host chromosomal DNA. Integration occurs throughout the host cell genome, but target site selection is not random. Each subgroup of retrovirus is distinguished from the others by attraction...

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Detalhes bibliográficos
Main Authors: Santoni, Federico Andrea, Hartley, Oliver, Luban, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991247/
https://ncbi.nlm.nih.gov/pubmed/21124862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001008
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