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Deciphering the Code for Retroviral Integration Target Site Selection

Upon cell invasion, retroviruses generate a DNA copy of their RNA genome and integrate retroviral cDNA within host chromosomal DNA. Integration occurs throughout the host cell genome, but target site selection is not random. Each subgroup of retrovirus is distinguished from the others by attraction...

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Détails bibliographiques
Auteurs principaux: Santoni, Federico Andrea, Hartley, Oliver, Luban, Jeremy
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991247/
https://ncbi.nlm.nih.gov/pubmed/21124862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001008
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