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Integration Site Selection by Retroviral Vectors: Molecular Mechanism and Clinical Consequences

Retroviral DNA integration into the host cell genome is an essential feature of the retroviral life cycle. The ability to integrate their DNA into the DNA of infected cells also makes retroviruses attractive vectors for delivery of therapeutic genes into the genome of cells carrying adverse mutation...

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Detalles Bibliográficos
Main Authors: Daniel, René, Smith, Johanna A.
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940482/
https://ncbi.nlm.nih.gov/pubmed/18533894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2007.148
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