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Dual action of neurokinin-1 antagonists on Mas-related GPCRs

The challenge of translating findings from animal models to the clinic is well known. An example of this challenge is the striking effectiveness of neurokinin-1 receptor (NK-1R) antagonists in mouse models of inflammation coupled with their equally striking failure in clinical investigations in huma...

詳細記述

保存先:
書誌詳細
出版年:JCI Insight
主要な著者: Azimi, Ehsan, Reddy, Vemuri B., Shade, Kai-Ting C., Anthony, Robert M., Talbot, Sebastien, Pereira, Paula Juliana Seadi, Lerner, Ethan A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053144/
https://ncbi.nlm.nih.gov/pubmed/27734033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89362
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