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Dual action of neurokinin-1 antagonists on Mas-related GPCRs
The challenge of translating findings from animal models to the clinic is well known. An example of this challenge is the striking effectiveness of neurokinin-1 receptor (NK-1R) antagonists in mouse models of inflammation coupled with their equally striking failure in clinical investigations in huma...
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Publicado no: | JCI Insight |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5053144/ https://ncbi.nlm.nih.gov/pubmed/27734033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89362 |
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