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Substance P activates Mas-related G protein–coupled receptors to induce itch
BACKGROUND: Substance P (SP) is linked to itch and inflammation through activation of receptors on mast cells and sensory neurons. There is increasing evidence that SP functions through Mas-related G protein–coupled receptors (Mrgprs) in addition to its conventional receptor, neurokinin-1. OBJECTIVE...
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| Publicado no: | J Allergy Clin Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5546940/ https://ncbi.nlm.nih.gov/pubmed/28219706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2016.12.980 |
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