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Mas-related G-protein coupled receptors and cowhage-induced itch

Cowhage is routinely used in human studies of histamine-independent itch. As such, it is of interest to understand its mechanism of action. The active component of cowhage is a cysteine protease called mucunain. As serine proteases can activate members of the protease-activated receptor (PAR) family...

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Détails bibliographiques
Publié dans:J Invest Dermatol
Auteurs principaux: Reddy, Vemuri B., Azimi, Ehsan, Chu, Lei, Lerner, Ethan A.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794532/
https://ncbi.nlm.nih.gov/pubmed/28988117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2017.05.042
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