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Metformin displays in vitro and in vivo antitumor effect against osteosarcoma

PURPOSE: Patients with unresectable, relapsed, or refractory osteosarcoma need a novel therapeutic agent. Metformin is a biguanide derivative used in the treatment of type II diabetes, and is recently gaining attention in cancer research. METHODS: We evaluated the effect of metformin against human o...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Korean J Pediatr
Päätekijät: Ko, Yunmi, Choi, Aery, Lee, Minyoung, Lee, Jun Ah
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Korean Pediatric Society 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5052136/
https://ncbi.nlm.nih.gov/pubmed/27721842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3345/kjp.2016.59.9.374
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