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Caffeine citrate enhanced cisplatin antitumor effects in osteosarcoma and fibrosarcoma in vitro and in vivo

BACKGROUND: While multiagent chemotherapy has dramatically improved the prognosis of sarcoma, the novel chemotherapeutics have hardly developed over the past 30 years. Caffeine can induce apoptosis, delays in cell cycle progression and can enhance the cytocidal effects of anti-cancer agents. Citrate...

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Podrobná bibliografie
Vydáno v:BMC Cancer
Hlavní autoři: Abe, Kensaku, Yamamoto, Norio, Hayashi, Katsuhiro, Takeuchi, Akihiko, Tsuchiya, Hiroyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6631922/
https://ncbi.nlm.nih.gov/pubmed/31307409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5891-y
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