Humanizing NOD/SCID/IL-2Rγnull (NSG) mice using busulfan and retro-orbital injection of umbilical cord blood-derived CD34(+) cells

BACKGROUND: Humanized mouse models are still under development, and various protocols exist to improve human cell engraftment and function. METHODS: Fourteen NOD/SCID/IL-2Rγnull (NSG) mice (4‒5 wk old) were conditioned with busulfan and injected with human umbilical cord blood (hUCB)-derived CD34(+)...

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Publicado en:Blood Res
Main Authors: Kang, Young Kyung, Ko, Yunmi, Choi, Aery, Choi, Hyeong Jwa, Seo, Jin-Hee, Lee, Minyoung, Lee, Jun Ah
Formato: Artigo
Idioma:Inglês
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2016
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828526/
https://ncbi.nlm.nih.gov/pubmed/27104189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5045/br.2016.51.1.31
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