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Antitumor effect of focal adhesion kinase inhibitor PF562271 against human osteosarcoma in vitro and in vivo

Focal adhesion kinase (FAK) overexpression is related to invasive and metastatic properties in different kinds of cancers. Target therapy by inhibiting FAK has achieved promising effect in some cancer treatments, but its effect in human osteosarcoma has not been well studied. In the present study, w...

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Bibliografische gegevens
Gepubliceerd in:Cancer Sci
Hoofdauteurs: Hu, Chuanzhen, Chen, Xu, Wen, Junxiang, Gong, Liangzhi, Liu, Zhuochao, Wang, Jun, Liang, Jing, Hu, Fangqiong, Zhou, Qi, Wei, Li, Shen, Yuhui, Zhang, Weibin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5497929/
https://ncbi.nlm.nih.gov/pubmed/28406574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13256
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