LasR Variant Cystic Fibrosis Isolates Reveal an Adaptable Quorum-Sensing Hierarchy in Pseudomonas aeruginosa

Chronic Pseudomonas aeruginosa infections cause significant morbidity in patients with cystic fibrosis (CF). Over years to decades, P. aeruginosa adapts genetically as it establishes chronic lung infections. Nonsynonymous mutations in lasR, the quorum-sensing (QS) master regulator, are common in CF....

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Detaylı Bibliyografya
Yayımlandı:mBio
Asıl Yazarlar: Feltner, John B., Wolter, Daniel J., Pope, Christopher E., Groleau, Marie-Christine, Smalley, Nicole E., Greenberg, E. Peter, Mayer-Hamblett, Nicole, Burns, Jane, Déziel, Eric, Hoffman, Lucas R., Dandekar, Ajai A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050340/
https://ncbi.nlm.nih.gov/pubmed/27703072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01513-16
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