Evolution of the Pseudomonas aeruginosa quorum-sensing hierarchy

The bacterial pathogen Pseudomonas aeruginosa activates expression of many virulence genes in a cell density-dependent manner by using an intricate quorum-sensing (QS) network. QS in P. aeruginosa involves two acyl-homoserine-lactone circuits, LasI-LasR and RhlI-RhlR. LasI-LasR is required to activa...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Kostylev, Maxim, Kim, Daniel Y., Smalley, Nicole E., Salukhe, Indraneel, Greenberg, E. Peter, Dandekar, Ajai A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2019
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452656/
https://ncbi.nlm.nih.gov/pubmed/30850547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1819796116
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