Epigenetic silencing of miR-124 prevents spermine oxidase regulation: Implications for Helicobacter pylori-induced gastric cancer

Chronic inflammation contributes to the development of various forms of cancer. The polyamine catabolic enzyme spermine oxidase (SMOX) is induced in chronic inflammatory conditions, including Helicobacter pylori-associated gastritis, where its production of hydrogen peroxide contributes to DNA damag...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Murray-Stewart, Tracy, Sierra, Johanna C., Piazuelo, M. Blanca, Mera, Robertino M., Chaturvedi, Rupesh, Bravo, Luis E., Correa, Pelayo, Schneider, Barbara G., Wilson, Keith T., Casero, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050049/
https://ncbi.nlm.nih.gov/pubmed/27041578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.91
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