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Spermine oxidase, a polyamine catabolic enzyme that links Helicobacter pylori CagA and gastric cancer risk

We have recently reported that Helicobacter pylori strains expressing the virulence factor cytotoxin-associated gene A (CagA) stimulate increased levels of spermine oxidase (SMO) in gastric epithelial cells, while cagA(–) strains did not. SMO catabolizes the polyamine spermine and produces H(2)O(2)...

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Autores principales: Chaturvedi, Rupesh, de Sablet, Thibaut, Peek, Richard M., Wilson, Keith T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337125/
https://ncbi.nlm.nih.gov/pubmed/22555547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/gmic.19345
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